The link between type 2 diabetes and cardiovascular disease

Cardiovascular disease is the no.1 cause of morbidity and mortality in people with diabetes globally1

In people with diabetes, approximately two-thirds of deaths are attributable to cardiovascular disease.
 

Compared with people without diabetes, there is up to:
 

Cardiovascular disease is the largest contributor to the direct and indirect costs of diabetes.4


Multiple mechanisms drive accumulated risk for cardiovascular disease morbidity in patients with diabetes

Recent studies have looked at the following mechanisms:

  • Atherosclerotic plaques in patients with diabetes tend to be more unstable than in people without diabetes, leading to greater risk for plaque rupture and thrombosis5
  • Linear progression of cardiovascular disease over time6,7
  • Worsening age-related changes in cardiovascular function increase morbidity8

o In 2011, heart disease or stroke was reported in 28.3% of people with diabetes aged 35 to 64, 43.1% aged 65 to 74 and 55.1% aged 75 or older9


Diabetes is a disease that greatly impacts cardiovascular disease risk

Cardiovascular risk increases with age, additional comorbidities and diabetes progression.8